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These impairments can be observed in day-to-day activities, such as minor loss of sense of smell, monotonous speech, trivial hoarseness in voice, and increased slowness in daily routine chores

The reaction mixture was stirred at room temperature for 24 h

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Acknowledgements The authors wish to thank Ivana igov Perunsk, Lucia Nehodov and Marcela Vrostkov for their excellent technical help in the lab

When combined with scalp microneedling, GHK-Cu penetrates directly to the follicle level through needle-created channels