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However, both Siglec-1 + marginal zone and MARCO + metallophilic macrophages (MZM and MMM) 58 formed similar structures in the spleen of Gclc fl/fl Mb1-Cre + mice compared to controls (Supplementary Fig

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Supplementary Figure 1a-f ), which were enriched in multiple metabolic processes, among which amino acid metabolisms (e.g., glutamate metabolism, glycine and serine metabolism, and cysteine and methionine metabolism) being the most significantly downregulated pathways upon LDHB KD ( Figure 1b )

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What They Found 1