The inhibitory receptor siglec-8 interacts with FcRI and globally inhibits intracellular signaling in primary mast cells upon activation
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In this condition, the airway produces excess mucus and becomes swollen (inflamed), causing the person to have a long-lasting cough while trying to get rid of the excess mucus
it can also worsen health complications such as low blood sugar, impaired coordination, cognitive abilities, and functioning, as well as liver damage