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The transcription factor Nrf2 is a potent transcriptional activator that plays a central role in the inducible expression of many cytoprotective genes in response to oxidative and electrophilic stresses ( Figure 1 )

[7] [9] As with all parenteral medications, administration should be avoided in the presence of local or systemic infection at the injection site

Am J Physiol Heart Circ Physiol 2021;320:H549-62.ArticlePubMed 82

Table 2: Effect of 6-weeks oral treatment with H.pylori eradication therapy(1), nizatidine alone(2) and in combination with either vitamin E(3) or thioctic acid(4) or a combination of both(5) on plasma MDA conc

Cell Death & Disease 2023 In vitro studies report glutathione protects cells from oxidative cytotoxicity in part by activating the Nrf2/HO-1 antioxidant-response pathway

O'Dwyer PJ, LaCreta F, Nash S, Tinsley PW, Schilder R, Clapper ML, Tew KD, Panting L, Litwin S and Comis RL (1991)