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Another microbiota-targeted compound is ganoderic acid, derived from Ganoderma lucidum

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- We need to establish the clinical relevance of microbiome profiles

On the other hand, the liver tissue section of the MTX + MCP group revealed a normal distribution of the fibrous tissue with a dilated portal vein (Figure 2A)

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however, these studies frequently lack methodological rigor, appropriate controls, and adequate statistical power to confirm efficacy