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One study looking at subfertile men who received zinc sulfate supplementation showed a significant increase in sperm concentration: Approximately 18.5 million sperm per milliliter ( P = .02 ) compared to baseline

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(5) Yu-Xiang Kong, Zhi-Shuai Li, Yuan-Bo Liu, Bo Pan, et al (2025) FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation Communications Biology, volume 8, Article number: 299 (2025)