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Western Blot After the drug treatment, the proteins from the cultured SGNs were extracted with radioimmunoprecipitation assay buffer (RIPA) buffer (Protein Biotechnology, China)

Ethical approval This article does not contain any studies with human participants or animals performed by any of the authors, except for those published previously and approved by respective ethic committees

12 ] In humans, melatonin production often declines with age, which may contribute to sleep disturbances and disruptions in normal biological timing

In addition, the cytokines IL-1, IL-6 and IFN- may be potential targets for treating patients with IBD who do not respond to anti-TNF therapy

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Potential therapeutic candidates for age-related macular degeneration (AMD)