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Wink et al., 2016

This leads to severe oxidative stress, lipid peroxidation, and catastrophic damage to cellular membranes and mitochondrial DNA, triggering systemic inflammation

Correlation of Log 10 normalized RNA counts of all transcripts ( h ) and selected basal cell, differentiation, cell cycle and cell fate modulator mRNAs ( i ) 45 , 51

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Acetaminophen Toxicity Results in Site-Specific Mitochondrial Damage in Isolated Mouse Hepatocytes

Matrix metalloproteinase-10 is upregulated by thrombin in endothelial cells and increased in patients with enhanced thrombin generation