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Thomas DA, Cortes J, Giles F, O'Brien S, Faderl S, Garcia-Manero G, Beran M, Koller C, Andreeff M, Kornblau S, Keating M, Kantarjian H

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Mice were single-housed during the fasting period and the duration of the test

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Additionally, within this observational timeframe, individuals undergoing metformin intervention manifested notable reductions in concentrations of advanced oxidation protein products (AOPP) and advanced glycation end products (AGE) in comparison to the control group (Mirmiranpour et al., 2013)