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Additionally, the TRAF1-C5 gene, an immune-related gene, functions in the initiation and progression of inflammation, offering predictive value for assessing the severity of RA, particularly concerning joint destruction [28]

The mitochondria are the cells' energy generators

GPX4, which is an antioxidant enzyme that reduces ROS, can prevent the formation of toxic lipid peroxides (25), we examined whether 5-FU or AZ628 affects GPX4 expression

Hattori, S.-I