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ClO reacts rapidly with glutathione to give products that glutathione reductase cannot reduce (Carr and Winterbourn 1997)

doi: 10.1093/jn/133.5.1302 54 YooWZiebaJKFoegedingNJTorresTPSheltonCDShealyNGet al

51 The lung is particularly at risk from oxidative damage as it is exposed to oxygen, oxygen radicals produced by alveolar macrophages, inhaled environmental and blood-borne toxins, including cigarette smoke and atmo-spheric pollutants

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While oral forms are generally safe, they can cause mild stomach discomfort in rare cases

An investigation from Farshbaf-Khalili et al., in Iran (2022), in a triple-blind, randomized controlled trial, examined the effects of curcumin on oxidative stress markers in postmenopausal women 4060 years of age