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The time to steady state, which is a function of t 1/2eff , is an important consideration in determining appropriate dose adjustments for patients receiving tacrolimus

doi: 10.1016/j.retram.2022.103362 25 HuguenardC

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Nguyen VD, Han JW, Choi YJ, et al

One of them, a large published review by doctors from Harvard, Duke and the University of Colorado concluded one explanation for the increased prevalence of autism is that increased exposure to acetaminophen, exacerbated by inflammation & oxidative stress, when given to a child at a susceptible timing or with susceptible genetics and epigenetics is neurotoxic in babies and small children

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