4-HNE represents a highly reactive lipid peroxidation byproduct that induces cellular damage by interacting with proteins, DNA, and other cellular components through iron- and oxygen-mediated chain-breaking reactions (7)
In other cases, the reactive forms of oxygen (singlet oxygen, the superoxide and hydroxyl radicals, hydrogen peroxide), that are not coped with by the natural detoxifying mechanisms, can react with biological structures and impair their physiological function
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High red and processed meat consumption is associated with non-alcoholic fatty liver disease and insulin resistance
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On the one hand, they contain glucosinolates, which can be metabolized into goitrogenic compounds such as goitrin and thiocyanate (SCN ), which competitively inhibit iodide uptake by thyroid follicular cells (167, 168)