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The combined supplementation significantly increased plasma nitrite and NOx concentrations 30 minutes after exercise, while neither supplement alone achieved this effect

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However, coffee may also contain very small amounts of a chemical called acrylamide, considered a possible carcinogen

doi:10.1016/S0140-6736(23)01163-7

10.1016/j.jep.2024.117813 98 LoncarevicI.MutluS.DzepicM.KeshavanS.Petri-FinkA.BlankF.et al (2024)

Cilostazol elevates intracellular cyclic nucleotides, and increased amounts of these nucleotides have been demonstrated to diminish ROS production and cellular dysfunction