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Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis

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Based on the average weight loss as reported by patients without diabetes who reached and maintained a dose of 2.4 mg/week of GLP-1 treatment, along with a reduced-calorie diet and increased physical activity

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However, overexpression of myo-inositol oxygenase (MIOX) can aggravate cisplatin-induced ferroptosis in the context of AKI by downregulating GPX4 activity, promoting lipid peroxidation and increasing the ferritinophagy rate [172]