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Moorthy M, Fakurazi S, Ithnin H (2008) Morphological alteration in mitochondria following diclofenac and ibuprofen administration

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NMDA Receptor Modulation In brain research models, DSIPs effects appear to be at least partly mediated via NMDA receptors a glutamatergic ionotropic receptor family central to synaptic plasticity, learning and memory, and excitatory neurotransmission

Severe effects warrant immediate discontinuation