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While there is no direct evidence of TTC5 interaction with MYCN in NB, both proteins are direct interactors of the histone acetyltransferase p300 (74, 75)

[8] In addition, drugs that affect blood cell production, such as certain chemotherapy agents or some HIV medications, may blunt the benefits of vitamin B or alter blood counts

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Although it is difficult to conclude that ROS are the primary cause of apoptosis in this context, it is more likely that both DPI and MitoQ cause irreversible damage to OXPHOS in MNA cells (67)

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