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10 Notably, a novel cNADK mutant, NADK-I90F, is found in pancreatic ductal adenocarcinoma cancer (PDAC) patients

95% confidence interval, 11.2 to 9.5

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For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors Access this article Similar content being viewed by others Data Availability The datasets used and analyzed during the current study are available from the corresponding author upon reasonable request

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Additionally, the protective effects of estrogens in PD are also related to the activation of the mitogen-activated protein kinase (MAPK) signaling pathway and the consequent upregulation of Bcl-2, as demonstrated in dopaminergic cells in mesencephalic slice cultures (Wang et al., 2011)