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In the same context, it showed elevation in serum estradiol levels with subsequent disturbance of T/E2 ratio among smokers compared with nonsmokers

The Beis Meir in his commentary on Shulchan Aruch contended that since tobacco and its components are wholly inedible before Pesach, it should be permitted on the basis that it is nifsal meachilas kelev (not fit for a dog

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