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L02 cells were transfected with GSTA1 or control plasmids for 36 h and further treated with or without bicyclol for 12 h
The addition of 75 g/kg methyl-cobalamin injected twice weekly for one month further normalised GSH:GSSG
Collectively, these advances establish a strong foundation for next-generation, precision-guided, and immunologically synergistic multimodal therapy (see Table 2)
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Free radicals are unstable atoms or molecules generated during normal bodily processes like metabolism and exercise or from environmental toxins such as pollution and cigarette smoke