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In conclusion, loss of the BBB integrity, caused by the damage of any of its specific cellular component, leads to its functional failure and in turn to cerebrovascular dysfunction, neuroinflammation and neurodegeneration, contributing also to AD development (Desai et al., 2007

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This article probes the mechanism of the thiol-disulphide oxidoreductase DsbD and provides an elegant example of the intra-protein transfer of disulphide bonds that seems be important in the function of several proteins involved in cellular protein oxidation and reduction

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[DOI] [PubMed] [Google Scholar] 297.Tlak Gajger I., Smodi kerl M.I., otari P., uran J., Sikiri P., Vlaini J