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Several mechanisms have been proposed for menstrual migraine, including reduced magnesium levels, platelet dysfunction, impaired central serotonin modulation, and impaired prostaglandin release (115)

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Despite the known direct association of p300 with NRF2, p300 is only detected at a small subset of group II gene promoters despite high occupancy of NRF2

4 Glutamatergic-Targeted Therapies Here, we provide a brief historical perspective of NMDA-targeted therapies for depression, focusing on treatments that progressed into phase 3 clinical trials (Fig

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