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1A), voluntarily consumed biological macromolecules serving as metabolic fuels are categorized into proteins, carbohydrates, lipids, and conjugates (which further break down into the previous three categories), as well as other that include nucleic acids and small metabolites such as pyruvate, lactate, and acetate 6

At age 55 years and older, the majority of symptomatic TTR-V30M gene carriers in northern Sweden are male

Studies have shown that rapamycin treatment can prolong the life span of invertebrates and mice, slow down or even reverse a variety of age-related changes in mice including arterial function changes, cardiomegaly, periodontitis, immunosenescence, and cognitive decline (Li et al., 2014

Therapeutic approaches in the improvement of cognitive performance in Down syndrome: Past, present, and future

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Mingori and colleagues compared the effect of caffeine with guarana extract in middle-aged rats, finding that only caffeine produced an anxiolytic effect and improved memory, an effect associated with neuroprotection in the hippocampus and striatum [31]