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After establishing a 5-day PCPA-induced insomnia model, treatments were administered over a subsequent 7-day period

DONT use the nasal spray within 1 hour of using other nasal decongestants or allergy sprays, as this can wash the medicine away before it absorbs

Optionally, a controlled-release formulation includes otoprotective agents, such as antioxidants, alpha lipoic acid, calcium, fosfomycin or iron chelators, to counteract potential ototoxic effects that may arise from the use of specific therapeutic agents or excipients, diluents, or carriers

This lack of approval means they haven't been proven safe or effective through rigorous clinical trials

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