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Dihexa binds with high affinity to HGF and both dihexa and its parent compound Norleucine 1-AngIV induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF-dependent cell scattering

DOI: 10.1073/pnas.0406491101 Brines M et al

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Thus, successful wound healing in infection relies on a tightly regulated sequence of phagocyte activation, polarization, and metabolic adaptation, ensuring efficient pathogen elimination while enabling timely transition to tissue repair