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These are predominantly mild to moderate and transient

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Free Radic Biol Med 49:14941504 Sedlak J, Lindsay RH (1968) Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellmans reagent

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As the positive control group, the second group received only 1 mL of distilled water by gavage, the third group received a daily dose of safflower extract via stomach gavage at a dose of 200 mg/kg body weight (Karami et al., 2017), and the fourth group (G4) received a daily oral dose of 20 mg/kg body weight atorvastatin dissolved in distilled water ( ad libitum