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A mitochondria-targeted covalent organic framework (COF) prodrug that is selectively activated by high intramitochondrial GSH levels was shown to trigger catalase collapse within the organelle, thereby amplifying local chemodynamic therapy (CDT) through enhanced ROS accumulation and mitochondrial dysfunction

Jang, D

Funding This work was supported by Tropical Medicine and Biology Platform, School of Science and School of Engineering, Monash University Malaysia

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The interaction between inflammation and oxidative status is well understood in preterm infants, especially in neonatal morbidities, as commented elsewhere (10)

Human studies targeting the alleviative effects of honey in counteracting chemotherapy or radiotherapy side effects were also prioritized