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Nicotine also produces long-term effects on the dopamine system, which is involved in reward, mood and addiction

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Int J Scientific Research in Environ Sci 3:915 Montalvo MF, Sampaio LLG, Gomes HHF, Malafaia G (2019) An insight into the cytotoxicity, genotoxicity, and mutagenicity of smoked cigarette butt leachate by using Allium cepa as test system

An FDA report states: Nicotine disrupts the formation of brain circuits that control learning, attention and susceptibility to addiction