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doi: 10.1186/s12931-019-1164-1 155 CuiJWangYTianXMiaoYMaLZhangCet al

95 Although the antioxidant properties of uric acid have long been recognized, its pro-inflammatory effects complicate its physiological significance and clinical relevance

Kadota Y, Toriuchi Y, Aki Y, Mizuno Y, Kawakami T, Nakaya T, et al

E3 ligases are the most diverse and functionally specialized components of the UPS and are responsible for substrate recognition and the final transfer of ubiquitin to target proteins

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