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GHK-Cu's distinctive feature in this broader landscape is its dependence on copper coordination chemistry rather than on direct receptor engagement

[PubMed] [PMC] Das DN, Panda PK, Sinha N, Mukhopadhyay S, Naik PP, Bhutia SK (2017) DNA damage by 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced p53-mediated apoptosis through activation of cytochrome P450/aryl hydrocarbon receptor

In a similar murine model of AR, in addition to decreasing symptoms after nasal challenge, quercetin was able to reduce Th17 cells, increase Treg cells, as well as promote Th1/Th2 balance, by reducing IgE and IgG1 levels and elevating IgG2 levels and the IgG2a/IgG1 ratio in a dose-dependent manner

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