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Replicative BCVs (rBCVs) emerge through fusion with the endoplasmic reticulum (ER), where they acquire ER markers such as calnexin and calreticulin, where Brucella replicates and evades immune responses (Figure 1B) (52)

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Proc Natl Acad Sci U S A 91:12614, PMID: 8108398 Kuchino Y, Mori F, Kasai H, Inoue H, Iwai S, Miura K, Ohtsuka E, Nishimura S (1987) Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

A randomized phase II trial of CRLX101 in combination with bevacizumab versus standard of care in patients with advanced renal cell carcinoma

Women demonstrate lower prevalence of T2D and prediabetes in younger ages as well as decreased mortality due to diabetes compared to males despite higher BMI in women

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