John's wort Mechanism of Action: Inducers of Intestinal P-glycoprotein (& hepatic cyt-P450) Background: P-glycoprotein is a membrane-bound protein that is thought to play a protective role, functioning to prevent entry and promote removal of xenobiotics (foreign compounds) from the body by translocating them from intracellular to the extracellular environment
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Disease burden associated with alpha-1 antitrypsin deficiency: systematic and structured literature reviews
LDL-C remains central to guidelines, trial interpretation, and therapeutic targets
As the impact of diabetes pathogenesis has been intensively studied, there is growing evidence that people with impaired glucose tolerance and diabetes have an increased risk of developing cognitive dysfunction compared to healthy individuals, and a 50% increased risk of dementia in type 2 diabetes (T2DM) (2)
Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis
