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JCIS Open 15:100118

Its primary research application is as a pharmacological probe to selectively activate IGF1R in cell culture systems where IGFBP interference would otherwise complicate interpretation

The most frequently reported adverse effects are gastrointestinal: nausea, vomiting, and diarrhea, which in published RCTs often occurred at rates similar to or only modestly above placebo

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(4) the ability to promote stem cell proliferation, differentiation, and neurogenesis, and encourage synaptogenesis in memory related brain structures

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