10.1046/j.1471-4159.2002.00837.x J
Its one way the body reacts to allergens and other inflammatory triggers, such as pet dander, pollen, plants, sunlight, emotional stress, and certain foods
It's gentle enough for everyday use, but always start with a patch test to ensure your skin responds well to it
Although there is no evidence of direct SIRT1 agonism, urolithin A is a well described mitophagy activator (63, 66, 67), contributing to improved mitochondrial efficiency and redox balance, which can indirectly improve SIRT1 expression and activity (68)
Even the review paper summarizing this study noted the results are not overly informative and reliable due to the lack of objective measures
But behind every number is a structural decision