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Study procedure Rats were deeply anesthetized using pentobarbital at a dose of 50mg/kg

The nasal route facilitates non-invasive administration, avoiding the need for injections or complex delivery systems, which may simplify protocol designs during experimental procedures

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Novo Nordisk is also continuing to run additional studies, including testing higher doses, to better understand the treatments full potential

Ozone Therapy delivers ozone, a highly concentrated form of oxygen, either into the blood by IV infusions or into damaged tissue through injections

For a loading protocol of 2.5 mg twice per week, reconstituting with 2 mL gives 2.5 mg/mL, so each 2.5 mg dose is 100 units (the full syringe)