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Results of a Randomized Phase III Study

Animal studies further confirm these anti-inflammatory effects, with high-fat-fed rats exhibiting reduced macrophage infiltration, lower circulating pro-inflammatory cytokines, and improved lipid metabolism due to the inhibition of lipogenesis and enhancement of fatty acid oxidation (Limbad et al., 2024

This complete protein is exceptionally rich in cysteine and other glutathione precursors

In some embodiments, the otic formulation or composition comprises between about 1% to about 40% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

In comparison to control animals, HFD-fed mice demonstrated significantly lower GSH levels in the liver, whereas GSSG levels were significantly elevated (Fig

Martinoia et al., 2012)