For the typical isotretinoin patient (a teenager or young adult without cardiovascular disease, clotting disorders, or concurrent anticoagulant use), the combined antiplatelet burden of isotretinoin plus 1 to 3 g/day omega-3s does not reach a threshold where prophylactic dose reduction is warranted
it's an autoimmune condition where the body mistakenly attacks and destroys a protein called intrinsic factor
Nutritional yeast is an excellent source of niacin
not Unlike the patient with acute ingestion, management is determined by the patients presentation (N&V, abdominal pain, altered mental status)
Lymphocyte infiltration of exocrine glands, autoantibody production, and an imbalance in the inflammatory cytokine network drive disease progression, ultimately resulting in glandular dysfunction and multisystem involvement
PMID: 18177285