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Researchers should understand this context when sourcing materials and planning protocols

In contrast, participants in this study did not report any severe illnesses, suggesting that the fluctuations in protein levels associated with condition changes may be smaller than those observed in the aforementioned diseases

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You want to differentiate which one of them is causing the issue

doi: 10.1038/s41590-019-0442-x 143 BasuSHubbardBShevachEM

How to Achieve High-Quality Oocytes