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We also identify druggable targets within lactylation pathwaysincluding LDHA, p300/CBP, AARS1/2, and monocarboxylate transportersand highlight their translational potential in guiding combination therapies, biomarker development, and nanomedicine strategies

Unlike other NLRP3 modifications, ZDHHC12-mediated palmitoylation modification occurs late in the completion of inflammasome function, which acts as a brake to shut down the inflammasome (76)

Many in vitro and in vivo studies have reported the sulfur-containing compounds, allicin and ajoene, for their effective anticancer, anti-diabetic, anti-inflammatory, antioxidant, antimicrobial, immune-boosting, and cardioprotective properties

Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport