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342 Furthermore, exosomes can easily cross biological barriers, such as the blood-brain barrier (BBB), which has good application potential in extra-hepatic-targeted NADs delivery

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Collectively, these results indicate that at disease onset at peak of neutrophil influx and mast cell degranulation occurs in the knees and these precede the persistent inflammatory response that then occurs in the digits

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The first is compound-specific , and looking at how those studies were actually run is instructive