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Although one of the potential limitations of translating cortistatin-based therapies to the clinical practice is its peptidic nature and low stability in physiological fluids, the interest of the pharmaceutical industry in protecting it and improving its bioavailability has considerably increased lately
Furthermore, the directional structure CuTA-CMHT hydrogel proposed by the Dong team utilized high-precision digital lithography (DLP) to achieve controllable manufacturing of micro-groove array structures, as shown in Figure 4C [81]
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