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Its often recommended to get B12 injections once a month or once or twice a week

Use cautiously if you have liver or kidney concerns, since these organs process supplements

Important things to keep in mind include: Serum B12 levels should be normal for most people Methylmalonic acid (MMA) and homocysteine levels can show if B12 is really working, even if levels seem fine How symptoms change is also important When and How to Adjust Dosing Regimens Doctors might need to change the dose based on test results and how the patient is doing

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Apply it to clean skin that is dry or just barely damp, not dripping wet

We suggest daily injections for one week to quickly boost B12 levels