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Targeting dysregulated copper homeostasis represents a promising frontier in cardiovascular therapy, offering a mechanistic approach that is distinct from conventional treatments

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This conclusion requires validation in future studies with a larger sample size

After completion of the isoelectric focusing, the strip was equilibrated in the equilibration solution as described by Barraclough [37] and placed on a polyacrylamide gel for SDS-PAGE with a Protean II unit (Bio-Rad, USA) at a constant voltage (300 V)

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