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Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation
Furthermore, unsupervised gut microbiota-based clustering of SLE patients recognized patient subgroups that associated with immune phenotypes and disease activity, which justified the use of microbiota patterns to predict response to therapy (229)
Moreover, diverse extracellular molecular signals, including neurotransmitters, neurotrophins, extracellular matrix proteins, contact-mediated ligands, and secreted diffusible cues, shape neural circuit development and modulate brain connectivity during early life (Hamad et al., 2023)
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