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However, there are also some examples where the reaction occurs spontaneously

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Springer International Publishing, Cham, pp 227245 Ando N, Morimoto K, Watanabe T et al (2004) Enhancement of central dopaminergic activity in the kainate model of temporal lobe epilepsy: implication for the mechanism of epileptic psychosis

Indeed, regular injections can boost energy levels and help with weight loss and mood