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J Microbiol Immunol Infect
The preserved pulsatile pattern is critical as it maintains normal receptor function and cellular responsiveness to GH signaling
Nature 498 , 367370 (2013)
Similarly to hypertension, coronary artery disease, and cancer, allergies have been classified as lifestyle diseases ( Numerous epidemiological and clinical studies have shown that oxidative stress directly or indirectly contributes to the risk of lifestyle diseases ( - ), the strongest oxidizing agent in vivo ( According to recent research, oxidative and nitrosative stress plays a key role in the pathogenesis of respiratory (including asthma) and skin allergies (AD, urticaria) (27)
A shift in focus from end-stage pathology to early intervention and neuronal preservation will be essential to transform the management of AD and improve outcomes for millions of affected individuals