Standard RDA: 2.4 mcg for adults Senior-Specific Needs: Often higher than 2.4 mcg due to absorption issues Recommended Intake for Seniors: At least 2.4 mcg, potentially much higher with supplementation Why the Standard 2.4 mcg May Not Be Sufficient The standard 2.4 mcg dosage might not be enough for seniors for a few reasons: Decreased Stomach Acid: Needed for B12 release from food Atrophic Gastritis: A common condition in older adults that makes it hard to absorb B12 Medication Interference: Some medicines can also block B12 absorption For those over 50, its best to get most of their vitamin B12 from supplements and fortified foods
Phase 3 data showed lower rates of nausea and vomiting compared to GLP-1 therapiespotentially better tolerated for some patients
Assuming that the crystal structure represents the minimum energy state, the goodness of the predicted structure can then be assessed by comparison with it
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Its a very limited study and I dont know how accurate it was, I assume that the b12 wasnt the little vials that we use today hence the smaller amounts injected in the study
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