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it forms water-soluble chelate compounds with iron that are rapidly eliminated by the kidneys

Others see changes in hair, skin, and nails, or feel that their metabolism has slowed down without an apparent reason

According to NICE Clinical Knowledge Summaries, the health consequences of untreated B12 deficiencyincluding irreversible neurological damage, megaloblastic anaemia, and cognitive impairmentfar outweigh the inconvenience of manageable acne

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However, research is still ongoing, and results may vary