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doi: 10.1186/s12906-017-1922-x 161

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It was developed in the laboratory of Joseph Harding at Washington State University as a metabolically stabilized analog designed to retain Ang IVs procognitive activity while overcoming the parent peptides short half-life and poor BBB permeability

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Preclinical studies demonstrated that AOD-9604 was generally safe after chronic oral application in rats and cynomolgus monkeys, with no genotoxic concerns identified

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