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In some of such embodiments, a low viscosity otic formulation or device is administered during an otic intervention

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If you overshoot, push the excess back into the water vial

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Cryo-EM data processing RELION-3.1.2 were used for all data processing to yield the polished particle stack that was subjected into cryoSPARC v4.4.1 for 3D reconstitution 28,29